Divergent clonal selection dominates medulloblastoma at recurrence
نویسندگان
چکیده
منابع مشابه
Subfrontal recurrence of medulloblastoma.
Twenty-nine patients received all or part of their therapy for medulloblastoma at our institution between 1983 and 1990. Review identified five patients (16%), with subfrontal recurrence, one of whom was initially treated by our staff. All five patients had undergone gross total tumor resection and irradiation of the entire neural axis. All subsequently died of uncontrolled tumor. Four recurren...
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To optimize the search of the clonal selection algorithm for the optimal solution, the selection operator is improved and a novel clonal selection algorithm is designed. The selection operator is compared with such selection operators as Roulette Wheel Selection operator, Tournament Selection operator, and Sampling Selection operator. The selection operator is improved to increase the accuracy ...
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2068 Background: Greater than 70% of patients diagnosed with medulloblastoma today are cured. However, salvage therapy after recurrence remains widely varied. Survival after recurrence of medulloblastoma has not been reported in an unselected cohort of patients in the contemporary era. METHODS With approval of the Institutional Review Board, medical records were reviewed for 55 patients diagn...
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ژورنال
عنوان ژورنال: Nature
سال: 2016
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature16478